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Amdocal Plus 5 mg + 50 mg

Tablet

Generic: Amlodipine + Atenolol

Beximco Pharmaceuticals Ltd.

Therapeutic Class: Calcium Channel Blocker + Beta Blocker

Indications

Hypertension not adequately controlled by either drug alone. Hypertension with angina pectoris.

Pharmacology

Amlodipine relaxes arterial smooth muscle and lowers peripheral resistance; atenolol is a cardioselective beta blocker that reduces heart rate and cardiac output. Together they give additive blood pressure control, and atenolol offsets the reflex rise in heart rate.

Dosage & Administration

Adult: one tablet (amlodipine 5 mg with atenolol 25 mg or 50 mg) once daily, adjusted according to response, or as directed by the physician. Elderly: start with the lower strength.

Side Effects

Ankle swelling, headache, flushing, fatigue, dizziness, slow heart rate, cold hands and feet and gastrointestinal upset.

Precautions & Warnings

Do not stop suddenly. Use with caution in diabetes, renal or hepatic impairment, heart failure and peripheral vascular disease. Not recommended in pregnancy and breast-feeding unless advised.

Contraindications

Asthma or severe bronchospasm, marked bradycardia, second or third degree heart block, cardiogenic shock, uncontrolled heart failure, severe hypotension and hypersensitivity to either component.

Storage Conditions

Store below 30°C in a cool, dry place, away from light. Keep out of the reach of children.

This information is for reference only. Always consult a qualified doctor or pharmacist before taking any medicine.

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