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Candex 100000 units/ml

Suspension

Generic: Nystatin

Square Pharmaceuticals PLC.

Therapeutic Class: Polyene Antifungal

Indications

Oral and oropharyngeal candidiasis (oral thrush) and intestinal candidiasis.

Pharmacology

Nystatin binds to ergosterol in the fungal cell membrane, forming pores that cause leakage of cell contents and death of Candida. It is not absorbed from the gut and acts locally.

Dosage & Administration

Oral thrush (suspension 100,000 units/ml): 1 ml four times daily after food, held in the mouth before swallowing; usually for 7 days and continued for 48 hours after the lesions have cleared. Intestinal candidiasis (tablet): adult 500,000 units every 6 hours, doubled in severe infection, or as directed by the physician.

Side Effects

Nausea, vomiting and diarrhoea at high doses; irritation of the mouth. Rarely: skin rash, Stevens-Johnson syndrome.

Precautions & Warnings

Shake the suspension well before use. Continue for 48 hours after the symptoms have cleared. Not effective for systemic fungal infections.

Contraindications

Hypersensitivity to nystatin.

Storage Conditions

Store below 25°C in a cool, dry place, away from light. Keep out of the reach of children.

This information is for reference only. Always consult a qualified doctor or pharmacist before taking any medicine.

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