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Cortan 5 mg/5 ml

Solution

Generic: Prednisolone (Oral)

Incepta Pharmaceuticals Ltd.

Therapeutic Class: Corticosteroid (Glucocorticoid)

Indications

Inflammatory and allergic disorders such as asthma, severe allergic reactions, rheumatoid arthritis, lupus, inflammatory bowel disease, nephrotic syndrome and inflammatory skin diseases. Suppression of the immune system, as directed by the physician.

Pharmacology

Prednisolone is a synthetic glucocorticoid. It reduces inflammation by inhibiting the formation of inflammatory mediators such as prostaglandins and leukotrienes, and it suppresses the immune response.

Dosage & Administration

Adult: initially 10-20 mg daily (up to 60 mg daily in severe disease), preferably as a single dose in the morning after breakfast; usual maintenance 2.5-15 mg daily. Child: dose by body weight as directed by the physician. Use the lowest effective dose for the shortest time.

Side Effects

Indigestion, increased appetite, weight gain, fluid retention, raised blood pressure, raised blood sugar, mood changes and insomnia. Long-term use: osteoporosis, thin skin, cataract, glaucoma, adrenal suppression, increased risk of infection and slowed growth in children.

Precautions & Warnings

Do not stop suddenly after prolonged use; the dose must be reduced gradually. Use with caution in diabetes, hypertension, peptic ulcer, osteoporosis, glaucoma, psychiatric illness and past tuberculosis. Avoid contact with chickenpox or measles.

Contraindications

Systemic infection unless specific treatment is given, live vaccines in patients on immunosuppressive doses, and hypersensitivity to prednisolone.

Storage Conditions

Store below 30°C in a cool, dry place, away from light. Keep out of the reach of children.

This information is for reference only. Always consult a qualified doctor or pharmacist before taking any medicine.

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