Duphaston 10 mg

Conditions related to progesterone deficiency: painful periods, endometriosis, irregular cycles, secondary amenorrhoea, dysfunctional uterine bleeding and premenstrual syndrome. Threatened and habitual miscarriage, and infertility due to luteal insufficiency.

Dydrogesterone is an orally active progestogen that acts directly on the lining of the uterus, producing a complete secretory phase. It has no oestrogenic, androgenic or corticoid activity and does not suppress ovulation.

Painful periods: 10 mg 2 times daily from day 5 to day 25 of the cycle. Endometriosis: 10 mg 2 to 3 times daily from day 5 to day 25 of the cycle or continuously. Irregular cycles and premenstrual syndrome: 10 mg 2 times daily from day 11 to day 25 of the cycle. Threatened miscarriage: 40 mg at once, then 10 mg every 8 hours until the symptoms subside. Or as directed by the physician.

Headache, nausea, breast tenderness, menstrual disturbances and breakthrough bleeding.

To be used on the advice of a registered physician. The cause of abnormal bleeding should be established before treatment. Use with caution in liver disease, depression and conditions that worsened during a previous pregnancy or hormone treatment.

Hypersensitivity to dydrogesterone, undiagnosed vaginal bleeding, known or suspected progestogen-dependent tumours and severe liver disease.

Store below 30°C in a cool, dry place, away from light. Keep out of the reach of children.