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Revira 1 g

Tablet

Generic: Valacyclovir

Square Pharmaceuticals PLC.

Therapeutic Class: Antiviral (Nucleoside Analogue)

Indications

Shingles (herpes zoster); herpes simplex infections of the skin and mucous membranes, including first-episode and recurrent genital herpes; suppression of recurrent herpes simplex.

Pharmacology

Valacyclovir is a prodrug of acyclovir with much better oral absorption. It is converted in the body to acyclovir, which inhibits viral DNA polymerase.

Dosage & Administration

Shingles: 1 g three times daily for 7 days. Herpes simplex, first episode: 500 mg twice daily for 5-10 days; recurrence: 500 mg twice daily for 3-5 days. Suppression of recurrent herpes: 500 mg once daily. Reduce the dose in renal impairment.

Side Effects

Headache, nausea, vomiting, diarrhoea, abdominal pain, dizziness, skin rash. Rarely: renal impairment, confusion, hallucinations (mainly in renal impairment or the elderly).

Precautions & Warnings

Maintain adequate fluid intake. Use with caution in renal impairment and in the elderly. Start treatment as early as possible after symptoms appear. Use as directed by a registered physician and complete the advised course.

Contraindications

Hypersensitivity to valacyclovir or acyclovir.

Storage Conditions

Store below 30°C in a cool, dry place, away from light. Keep out of the reach of children.

This information is for reference only. Always consult a qualified doctor or pharmacist before taking any medicine.