Silcream 1%

Prevention and treatment of infection in second-degree and third-degree burns. Also for infected leg ulcers, pressure sores and skin graft donor sites.

Silver sulfadiazine slowly releases silver ions, which act on the bacterial cell membrane and cell wall, together with the antibacterial action of sulfadiazine. It is active against Gram-positive and Gram-negative bacteria, including Pseudomonas, and against yeasts.

After cleaning the wound, apply a layer about 3-5 mm thick with a sterile gloved hand or spatula once or twice daily; reapply to any area from which it has been removed. Continue until healing is satisfactory or the site is ready for grafting. For external use only.

Burning, itching or rash at the application site; greyish discolouration of the skin. Rarely: temporary fall in white blood cells, allergic reactions.

Use with caution in hepatic or renal impairment, G6PD deficiency and sulfonamide allergy. When used on large areas, monitor blood counts and renal function. Avoid contact with the eyes. Use as directed by a registered physician.

Hypersensitivity to silver sulfadiazine or sulfonamides. Pregnancy near term, premature infants and infants under 2 months (risk of kernicterus).

Store below 25°C in a cool, dry place, away from light. Keep out of the reach of children.