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Abetis 20 mg

Tablet

Generic: Olmesartan Medoxomil

ACI Limited

Therapeutic Class: Angiotensin II Receptor Blocker (Antihypertensive)

Indications

Hypertension, alone or in combination with other antihypertensive agents.

Pharmacology

Olmesartan medoxomil is a prodrug converted to olmesartan, an angiotensin II receptor blocker. It selectively blocks the AT1 receptor, causing vasodilation and reduced aldosterone secretion, which lowers blood pressure for 24 hours.

Dosage & Administration

Adult: 10-20 mg once daily; may be increased to a maximum of 40 mg once daily. May be taken with or without food.

Side Effects

Dizziness, headache, diarrhoea, fatigue, raised blood potassium and flu-like symptoms. Severe chronic diarrhoea with weight loss (sprue-like enteropathy) is rare.

Precautions & Warnings

Monitor kidney function and potassium in renal impairment, renal artery stenosis and the elderly. Correct volume depletion before starting. Report severe persistent diarrhoea. Not recommended during breast-feeding.

Contraindications

Pregnancy, hypersensitivity to olmesartan, biliary obstruction, and use with aliskiren in patients with diabetes or renal impairment.

Storage Conditions

Store below 30°C in a cool, dry place, away from light. Keep out of the reach of children.

This information is for reference only. Always consult a qualified doctor or pharmacist before taking any medicine.

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