Epitra 2 mg

All forms of epilepsy and myoclonus. Panic disorder.

Clonazepam is a benzodiazepine that enhances the inhibitory action of the neurotransmitter GABA in the brain, producing anticonvulsant, anxiolytic, sedative and muscle-relaxant effects.

Epilepsy: Adult: initially 1 mg (elderly 0.5 mg) at night for 4 nights, increased gradually over 2 to 4 weeks to a usual maintenance dose of 4 mg to 8 mg daily. Panic disorder: Adult: initially 0.25 mg 2 times daily, increased after 3 days to 1 mg daily, as directed by the physician. Child: the dose depends on age and body weight, as directed by the physician.

Drowsiness, fatigue, dizziness, muscle weakness, poor co-ordination and impaired concentration; increased salivation in children.

To be used only on the prescription of a registered physician. Causes drowsiness; avoid driving, operating machinery and alcohol. Prolonged use may cause dependence. Must not be stopped abruptly, as this may provoke seizures; the dose should be reduced gradually. Use with caution in the elderly, in respiratory disease, in hepatic or renal impairment and in pregnancy and lactation.

Severe respiratory insufficiency, sleep apnoea syndrome, severe hepatic impairment, myasthenia gravis, acute narrow-angle glaucoma and hypersensitivity to benzodiazepines.

Store below 30°C in a cool, dry place, away from light. Keep out of the reach of children.