Frabex 500 mg

Heavy menstrual bleeding (menorrhagia). Bleeding associated with excessive fibrinolysis, such as nosebleed, bleeding after dental extraction or surgery, and hereditary angioedema.

Tranexamic acid inhibits the activation of plasminogen to plasmin, preventing the breakdown of fibrin clots and thereby reducing bleeding.

Menorrhagia: Adult: 1 g 3 times daily for up to 4 days, starting when heavy bleeding begins; maximum 4 g daily. Local fibrinolysis: 1 g to 1.5 g 2 to 3 times daily. Injection: 0.5 g to 1 g by slow intravenous injection 2 to 3 times daily, given by a physician.

Nausea, vomiting and diarrhoea. Rarely disturbance of colour vision and blood clots; rapid intravenous injection may cause low blood pressure.

To be used on the advice of a registered physician. The dose must be reduced in renal impairment. Use with caution in blood in the urine from the upper urinary tract and in irregular menstrual bleeding of unknown cause. Stop treatment if any disturbance of vision occurs.

Active thromboembolic disease, history of venous or arterial thrombosis, severe renal impairment, history of convulsions and hypersensitivity to tranexamic acid.

Store below 30°C in a cool, dry place, away from light. Keep out of the reach of children.