Lipired 200 mg

Severe hypertriglyceridaemia. Mixed hyperlipidaemia when a statin is contraindicated or not tolerated, as an adjunct to diet.

Fenofibrate is converted to fenofibric acid, which activates the PPAR-alpha receptor. This increases breakdown of triglyceride-rich particles, markedly lowering triglycerides, moderately lowering LDL cholesterol and raising HDL cholesterol.

Adult: one 200 mg capsule once daily with a meal, or as directed by the physician. Reduce the dose in renal impairment.

Abdominal pain, nausea, diarrhoea, flatulence, raised liver enzymes, rash and muscle pain. Gallstones and pancreatitis are uncommon.

Monitor liver function and kidney function. The risk of muscle damage increases when used with a statin; report muscle pain. May increase the effect of warfarin.

Severe hepatic or renal impairment, gallbladder disease, pancreatitis (unless due to severe hypertriglyceridaemia), pregnancy, breast-feeding and photosensitivity reactions to fibrates or ketoprofen.

Store below 30°C in a cool, dry place, away from light. Keep out of the reach of children.