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Odrel Plus 75 mg + 75 mg

Tablet

Generic: Clopidogrel + Aspirin

Beximco Pharmaceuticals Ltd.

Therapeutic Class: Antiplatelet Combination

Indications

Acute coronary syndrome (unstable angina, heart attack) and after coronary stenting, in patients who need both clopidogrel and aspirin.

Pharmacology

Clopidogrel blocks the P2Y12 ADP receptor on platelets and aspirin blocks thromboxane A2 formation. Acting on two different pathways, the combination gives stronger inhibition of platelet aggregation than either drug alone.

Dosage & Administration

Adult: one tablet (clopidogrel 75 mg + aspirin 75 mg) once daily, after food. The duration of treatment is decided by the physician.

Side Effects

Bleeding (bruising, nosebleed, gastrointestinal bleeding), indigestion, abdominal pain, diarrhoea, nausea and rash.

Precautions & Warnings

The risk of bleeding is higher than with either drug alone. Use with caution in asthma, history of peptic ulcer, renal impairment and with anticoagulants or NSAIDs. Inform the doctor before any surgery.

Contraindications

Active bleeding, active peptic ulcer, bleeding disorders, severe hepatic impairment, hypersensitivity to either component or to NSAIDs, children under 16 years and the last trimester of pregnancy.

Storage Conditions

Store below 30°C in a cool, dry place, away from light. Keep out of the reach of children.

This information is for reference only. Always consult a qualified doctor or pharmacist before taking any medicine.

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