Anril SR 2.6 mg

Relief of an acute attack of angina pectoris (sublingual spray). Prophylaxis of angina (sustained release tablet, or spray before exertion).

Glyceryl trinitrate releases nitric oxide, which relaxes vascular smooth muscle. It dilates veins and, to a lesser extent, arteries, reducing the return of blood to the heart and its oxygen demand, and it dilates the coronary arteries.

Spray (400 mcg per spray): 1-2 sprays under the tongue at the onset of pain or before exertion; may be repeated after 5 minutes. If pain persists after 3 doses, seek urgent medical help. Sustained release tablet 2.6 mg: one tablet two to three times daily, swallowed whole, or as directed by the physician.

Throbbing headache, flushing, dizziness, postural hypotension and fast heart rate.

Sit down when using the spray, as dizziness may occur. Tolerance can develop with continuous use. Use with caution in hypothyroidism, recent heart attack, severe hepatic or renal impairment and with alcohol.

Use with sildenafil, tadalafil or vardenafil, severe hypotension, hypovolaemia, severe anaemia, raised intracranial pressure, aortic or mitral stenosis, hypertrophic cardiomyopathy and hypersensitivity to nitrates.

Store below 30°C, away from light and moisture; keep tablets in the original container. Do not pierce or burn the spray container. Keep out of the reach of children.