Nystat 100000 units/ml

Oral and oropharyngeal candidiasis (oral thrush) and intestinal candidiasis.

Nystatin binds to ergosterol in the fungal cell membrane, forming pores that cause leakage of cell contents and death of Candida. It is not absorbed from the gut and acts locally.

Oral thrush (suspension 100,000 units/ml): 1 ml four times daily after food, held in the mouth before swallowing; usually for 7 days and continued for 48 hours after the lesions have cleared. Intestinal candidiasis (tablet): adult 500,000 units every 6 hours, doubled in severe infection, or as directed by the physician.

Nausea, vomiting and diarrhoea at high doses; irritation of the mouth. Rarely: skin rash, Stevens-Johnson syndrome.

Shake the suspension well before use. Continue for 48 hours after the symptoms have cleared. Not effective for systemic fungal infections.

Hypersensitivity to nystatin.

Store below 25°C in a cool, dry place, away from light. Keep out of the reach of children.